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This leads to the formation of regenerative hepatic nodules encased in dense fibrous tissue, containing significantly higher levels of extracellular matrix proteins, particularly collagen types I, III, and IV, which hinder portal blood flow and elevate portal pressure, ultimately culminating in clinically significant portal hypertension in later disease stages ( In this comprehensive and evidence-driven review, the objective is to scrutinize the repercussions, diagnosis, and management of these often overlooked yet prevalent and challenging-to-treat symptoms encountered in cirrhosis (Figure 1)

Pseudocereals are highly nutritious and contains a huge range of compounds namely, phenolic acids, vitamins, flavonoids and fatty acids

Exhausted NK cells and cytokine storms in COVID-19: whether NK cell therapy could be a therapeutic choice

Organic solvents can also change the concentration of reactive species in the reaction mixture, which ultimately changes the product composition (Feng and Li, 2017)

Various methods have been investigated in attempts to overcome the harsh microenvironment that arises from cancer treatments, primarily with the aim of preventing reoccurrence and regenerating functional tissue