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As NAD+ levels naturally decline with age, stress, and lack of sleep, people may notice brain fog, fatigue, or difficulty concentrating

Various structurally related analogs of lipoic acid were developed, some of which are able to cross the bloodbrain barrier (Guillonneau et al., 2003

Fatigue can have many causes, so it should always be considered in context rather than attributed to the sinuses automatically

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JAMA Netw Open 2:e1910154

They also support metabolism, weight loss, and red blood cell production, benefiting individuals facing these challenges