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doi: 10.1126/sciadv.abf6780 29

Nanotechnology-based delivery systems including liposomes, SLNs, NLCs, and polymeric nanoparticles, partially overcome these limitations by enhancing dermal penetration, stability, and sustained release

Due to their favorable efficacy and tolerability profiles, SSRIs and SNRIs are widely recommended by international guidelines for managing perimenopausal affective symptoms (71,73)