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The reduction or omission of radiotherapy can result in an ineffective treatment, although this reduces the above-mentioned side effects (3, 4)

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

During the pre-diabetes stage, BB rats that are diabetes prone have increased intestinal permeability, altered tight junction proteins (specifically claudin 7), increased gut infiltration by neutrophils and decreased numbers of gut natural killer cells in comparison to BB rats which were diabetes resistant [168, 178]

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Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials

1 The key features of PH include excessive proliferation of pulmonary artery smooth muscle cells (PASMCs), increased extracellular matrix deposition, and inflammatory factor accumulation in the pulmonary vascular wall, all contributing to elevated pulmonary vascular resistance