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Regulation of gene transcription by thyroid hormone receptor agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

They first identified small molecules that activate SIRT1 such as resveratrol and studied how they improve metabolic function using a combination of genetic, enzymological, biophysical and pharmacological approaches

Biochem Biophys Res Commun (2014) 445(1):2305

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Do thyroid hormones enhance the production of melanin when the thyroid is in a normal state

This property is particularly beneficial in respiratory conditions characterized by thick, tenacious mucus