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Similarly, another work suggested that bromelain could regulate inflammatory cytokines and growth factors, including TNF-, IL-1, IL-6, and IFN (144)

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This aligns with reports that CPS1 is released into the bloodstream during acetaminophen-related acute liver injury in mice as well as humans and could potentially indicate prognosis 30,40

SIRT1 deficiency exacerbates synaptopathology and neurite retraction following noise exposure Noise-induced loss of synaptic connections between IHCs and ANFs, as well as the retraction of cochlear nerve terminals, are well-documented [34]

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