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J Hepatol 2017;66:610-618

PMID 19255021

Unlike many nutrients, B12 contains the mineral cobalt and has a uniquely complex structure that enables its diverse biological functions

Therapeutic Dosing for Deficiency Treatment For Vitamin B12 deficiency, you might need more than usual

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The patient then (1) programs infuse insulin at a basal rate of units per hour (but which can be adjusted), (2) delivers bolus infusions to cover meals (the patient pushes a button to deliver a bolus dose at meals), (3) changes delivery rates at specific times of the day (e.g., from 3 AM to 9 AM) to avoid early-morning hyperglycemia, and (4) overrides the set basal rate to allow for unexpected changes in activity such as early-morning exercise