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R., Epstein M., Frohlich E

PMID 11157536

Lancet Neurology 18 (3), 307318

Nonomiya J, Li KS, Babin BM, Mulvihill MM

When activated, the mast cells in the skin release mediators (histamines, tryptase, TNF-alpha, CXCL9, etc.) that cause inflammation, flushing, itching, or burning.[ref] Related article: Rosacea, underlying causes, genetic susceptibility Dermatographism and mast cell activation syndrome: In a survey of mast cell activation syndrome, dermatographism was found in 89% of the patients.[ref] Dermatographism is when you get welts or raised red lines when you scratch your skin lightly

l'acetil carnitina, in particolare, sarebbe importante per sostenere la sintesi di acetilcolina nelle situazioni in cui a causa di particolari patologie, come conseguenza di ipossia o invecchiamento vi una scarsa disponibilit di gruppi acetilici a causa di un alterato metabolismo glucidico