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Chem, 2021, 93, 1364113650

Pre-conception is always the best time to start, but decreasing risk factors and improving maternal health can be beneficial at any time in the pregnancy and even after birth while the infant is breast-feeding

doi:10.1093/humrep/dez305

Interestingly, since the adoption of IV NAC as the mainstay for the treatment of acetaminophen poisoning, the overall case-fatality has decreased from approximately 3% in the early 1970s to less than 1% in the 20082012 period [73, 88]