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Consequently, NRF2 dissociates from Keap1, escapes ubiquitination and degradation, accumulates in the cytoplasm, and ultimately translocates to the nucleus [85, 91, 92]

The human body's inability to extract energy from carbohydrates prompts it to use alternative sources of energy (93)

The script was deposited on GitHub and made publicly available ( Statistical analysis of obtained light/heavy (L/H) ratios for each cysteine (resembling ratios of reduced to oxidized cysteine residues) was performed in Perseus

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10.1021/acs.chemrev.7b00205 Chem

This mechanism is particularly relevant for Indian skin tones, where UV exposure and pollution significantly accelerate pigmentation concerns