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discovered that insomnia is associated with significant changes in the structure and function of gut microbiota, showing reduced diversity (both -diversity and -diversity) and altered microbial interactions in individuals with insomnia compared to healthy controls [213]

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Pathological Contribution of Dysbiosis and LGS to Autoimmune Diseases Exogenous (e.g., diet and drugs) and endogenous factors (e.g., antimicrobial peptides, S-IgA, and the mucin layer) are known to affect the gut microbial community