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Yamamoto John Wright Joseph W Harding The angiotensin IV analog norleual [Nle-Tyr-Leu--(CH(2)-NH(2))-Leu-His-Pro-Phe] has been shown recently to act as a hepatocyte growth factor (HGF)/Met antagonist capable of blocking the binding of HGF to the Met receptor, inhibiting HGF-dependent activation of Met, and attenuating HGF-dependent cellular activities

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Nature 603:124130

This has led researchers to explore whether the pair may produce complementary or synergistic signaling responses in selected in-vitro and in-vivo systems