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A fetus inherits the disease only if both parents pass on a mutated allele, demonstrating the concept of compound heterozygosity if the inherited mutations differ

Its complex pathogenesis involves dopaminergic neuron degeneration, -synuclein aggregation, neuroinflammation, oxidative stress, and mitochondrial dysfunction

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6.5 Fibrotic lung diseases Pulmonary fibrosis is a lung disease in which fibroblasts proliferate, a large amount of extracellular matrix accumulates leading to scarring, accompanied by inflammatory cell infiltration and destruction of alveolar wall structure (130, 131)

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