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In the STEP 3 trial, which combined Semaglutide with intensive behavioral therapy, the average weight reduction reached 16.0% (Wadden et al., JAMA 2021

Solitano V, DAmico F, Fiorino G, Paridaens K, Peyrin-Biroulet L, Danese S

Similarly, sesamol and sesaminol have shown neuroprotective effects in related models, often attributed to their ability to cross the bloodbrain barrier and act as free radical scavengers in the brain (68)

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A Safire fluorescence plate reader (Tecan US, Durham, NC) and black 96-well microtiter plates (Corning) were used for both sets of experiments

However, IF is often viewed as more sustainable because of its flexibility and user-friendly nature [17, 18]