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Furthermore, reactive astrocytes modulate acute neuroinflammation and repair the BBB in a CNS injury model, where their elimination resulted in impaired recovery

Proc Am Soc Clin Oncol 9:229, 1990

Abdullahi, Int

References: Moy FM, Hairi NN, Lim ERJ, Bulgiba A

Interestingly, there is no known receptor for klotho, rather there is a coreceptor formed by shed klotho, FGFR, and FGF23, which indicates that shed klotho is an enzyme-dependent active scaffold protein