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Abstract Only praziquantel is available for treating schistosomiasis, a disease affecting more than 200 million people

Healthy liver*

Using oxygen consumption as a measure of mitochondrial function, NRTIs were shown to induce a rapid decrease in mitochondrial fitness

These results indicate that TPC correlates more strongly with SOD and PPO, whereas TFC shows stronger correlations with GPX and CAT

(accessed on 10 December 2020) Ethics declarations Competing Interests The authors declare no competing interests

Plasmid Construction pGEX-4T-1 was modified with a 6XHis tag in front of a GST tag at the N-terminus, and the thrombin protease cleave sequence was replaced by the TEV protease cleave site by a one-step site-directed deletion and insertion method [59]