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Results Validation of Transfection of GSTP1 in HepG2 Cells To evaluate the role of GSTP1 in protecting against QIs-induced cellular perturbations, HepG2 cells were transiently transfected with a DNA construct containing the human GSTP1 cDNA behind a CMV-promoter

(2003) Detoxification of electrophilic compounds by glutathione S-transferase catalysis: determinanats of individual response to chemical carcinogens and chemotherapeutic drugs

Eukaryotic Cell 14, 335344

5 Antioxidants The therapeutic approaches currently being explored in FRDA are focused on either increase the levels of frataxin or mitigating the out-turn of frataxin loss