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Furthermore, analysis of gastrointestinal tumor data from the TCGA and GTEx database also revealed a statistically significant correlation between the expression of NF1 and YAP1 in CHOL (n = 36, R = 0.687, p = 3.70e-6), LIHC (n = 371, R = 0.690, p = 7.98e-54), PAAD (n = 179, R = 0.538, p = 1.87e-32), and STAD (n = 415, R = 0.640, p = 5.09e-22) (Additional file 6: Fig

If not diagnosed and treated, cats with DCM will either develop a life-threatening heart arrhythmia or progress to congestive heart failure, which is a medical emergency and can have a guarded prognosis

Animal model studies reinforce these findings, demonstrating lithiums capacity to reverse BD-like behaviors, normalize stress responses, and reduce hyperlocomotion

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doi: 10.1038/nrendo.2009.106 45 ChrousosGPKinoT