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To confirm that the intracellular GSH steady-state levels were not changing the rate limiting enzyme in GSH synthesis, -glutamylcysteine ligase (GCL), was examined and no increases in GCL expression were found (data not shown)

Here's what we've learned from working in peptide synthesis: purity and molecular integrity matter, but context matters just as much

Bradley-Whitman, M

Smallpox infection may be more serious among individuals who start off being GSH insufficient and only marginally able to produce IL-12, and IFNy, and to marshal smallpox-specific cytotoxic lymphocytes

Ohnishi K, Liu H, Liao Z, Yom SS, Jin H, Wei X, Allen PK, Tucker SL, Mohan R , Komaki R

Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress