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[60 ]Later in vitro and in vivo research, and well documented case reports, 63 suggest a vitamin C dose much higher than that used in the Pauling/Cameron studies can actually be cytotoxic to tumors without damaging normal cells

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As an occlusive, it forms a protective layer on the skin that locks in moisture and prevents transepidermal water loss (TEWL)

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28 Excessive ROS production leads to an oxidative inactivation of anti-proteases, alveolar epithelium damage, increased neutrophil retention and increased expression of various inflammatory mediators in the pulmonary microcirculation, aggravating the development of COPD