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Description

Abstract CD38 is a multifunctional transmembrane glycoprotein found in multiple tissues and overexpressed in many cancer cells, notably in hematological malignancies such as leukemia and multiple myeloma (MM)

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These studies suggest that, as a more fundamental mechanism to maintain cellular homeostasis, the function of V-ATPase-dependent autophagy may expand from pathological FL tumor cells to a broader physiological scenario