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Only advanced delivery methods, like liposomal technology, ensure that the antioxidant is actually absorbed and used by the body

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Conclusions and future directions Despite substantial progress, most evidence still derives from animal models, limiting clinical generalizability

Naringenin upregulates the anti-oxidative molecule GPX4 in rat spinal cords via the serine/threonine protein kinase AMPK/PGC-1 (peroxisome proliferator-activated receptor-gamma coactivator-1alpha, PGC-1) signaling pathway, alleviating mechanical allodynia caused by bone cancer in rats

as PD-patient fecal transplants into germ free animals triggered locomotor deficits, whereas fecal transplants from healthy human donors had no effect on locomotor function