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3D, with the prolongation of induction time, the expression of TAT-CcSOD1 in soluble form gradually increased, and there were no significant differences between 24 and 48 h

Neuroimmunomodulation 4 , 8490 (1997)

Despite major advances in our understanding of the metabolic and molecular mechanisms driving MASH, and considerable efforts in the development of drugs targeting lipid and carbohydrate metabolism, there is limited pharmacological therapy available for the treatment of MASH 6,7

Additionally, certain pro-oxidant compounds, such as quinones that participate in redox cycling, are ingested through diet

ME2 activity converts L-malate to pyruvate, which enters the tricarboxylic acid cycle (TCA) and then produces ATP via the respiration chain