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Selectivity of NNMT inhibitors Test compounds were screened in biochemical assays for activity against three structurally similar methyltransferases, including catechol-O-methyltransferase (COMT), DNA (cytosine-5)-methyltransferase 1 (DNMT1), and protein arginine methyltransferase 3 (PRMT3)

PMID 14752199.

However, they shouldnt be used too often, as long-term use may weaken tissues

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It is commonly studied in laboratory environments for its potential role in metabolic and biochemical research, particularly in pathways related to lipid metabolism and energy regulation

[DOI] [PubMed] [Google Scholar] 47.Khawaja I., Yingling K., Bukamur H., Abusnina W