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(2021) discovered that the mitigation of pro-inflammatory cytokine production (TNF-, IL-1, CXCL2 and MCP1) and endotoxin in the ileum, along with activation of the Nrf2/HO-1 pathway, could effectively restore ileum injury and barrier dysfunction associated with severe pancreatitis

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We here provide an overview to identify which genetic variants consistently associated with hematological toxicity and discuss limitations of current pharmacogenetic analyses and formulate directions for further research

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Patel R, Sushko K, van den Anker J, Samiee-Zafarghandy S

Men and women may yield different consequences based on dose, route, and biology

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