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"Annual Smoking-Attributable Mortality, Years of Potential Life Lost, and Economic Costs United States, 19951999", MMWR: Morbidity and Mortality Weekly Report 51, no

According to the Centers for Disease Control, Marijuana use directly affects the brain, specifically the parts of the brain responsible for memory, learning, attention, decision-making, coordination, emotion, and reaction time. Tetrahydrocannabinol (THC), the active ingredient in marijuana may remain in a persons body for days to weeks, depending on the amount and frequency of use

LDL levels can be elevated in individuals with low thyroid activity because T3 helps sensitize the LDL receptor on the cell membrane

Moreover, both nicotine and cocaine activate the brains reward system, flooding it with dopamine, a neurotransmitter associated with pleasure and motivation

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The environment is a key factor However, genetics is not the complete story