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AOD-9604 operates independently of GH receptors and doesn't engage the broader GH signaling cascade that produces IGF-1 elevation

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Animal studies have reported: reduced fat mass improved body composition increased energy expenditure However: there is currently insufficient human clinical evidence to confirm similar effects

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Basal lipolysis has been reported to be decreased in aFABP/ALBP/aP2-null mice compared with wild-type littermates (22, 49), and stimulated lipolysis in adipocytes isolated from these mice has also been shown to be attenuated (22, 110)