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Historical Background and Scientific Context Scientific interest in glutathione dates back to the early twentieth century following its identification as a naturally occurring intracellular peptide present throughout biological systems

mEPSC frequency declined even further when acivicin and MeAIB were coadministered, consistent with glutamate derived from the glutathione cycle contributing to maintenance of excitatory neurotransmission when glutamine supply is restricted (Fig

-L-Glutamyl-L-cysteinylglycine

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Mathieu F, Begaux F, Lan ZY, Suetens C, Hinsenkamp M