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The mechanism of histone phosphorylation may be due to the negative charge carried by the phosphate group neutralizing the positive charge on the histone, resulting in a decrease in the affinity between the histone and DNA (Rossetto et al., 2012)

Table of Contents: What are Glutathione injections good for

In particular, p53 inhibits SLC7A11 expression and reduces glutathione synthesis, making cancer cells susceptible to oxidative damage and sensitive to iron by increasing lipid peroxide levels [32,76,77]