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Higher concentrations dont necessarily work better and might cause sensitivity

Testosterone replacement therapy is not a set-it-and-forget-it prescription

Acknowledgements The authors thank Nick Rhodes from the Queensland Cyber Infrastructure Foundation (QCIF), Haojing Shao, and Enya Hermsen for their advice on bioinformatical analyses and computational assistance, Alastair McEwan and Mathias Jnsson for their editorial assistance on early drafts of the manuscript, and all members of the Degnan lab for their valuable discussions

10.1073/pnas.97.2.571 Proc

If homocysteine turns out to cause inflammation and therefore joint pain, then vitamin B12 supplementation would be a consideration

Individuals with such conditions require appropriate medical management from qualified healthcare providers, and glutathione therapy should only be considered as a complementary approach under professional supervision