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To overcome this issue, many researchers have attempted to combine daily injections of testosterone undecanoate with PDE5I, which has further improved the sustained therapeutic effect [182] and is recommended for ED patients with obesity and type 2 DM [183]

and Lauterburg, B.H

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The intricate relationship between apoptosis and neurotransmitter systems highlights the complexity of the neurobiological underpinnings of depression in the context of chronic alcohol use