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Tian, 2020

Alzheimer's disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation

After the drugs enter the cells through endocytosis, the toxic payload is released inside the cells through the action of lysosomes and subsequently exerts cell-killing effects 88

For skin brightening, some protocols suggest 2-3 injections per week for 1-3 months

110,489 Spesolimab is a novel humanized selective antibody that blocks the IL-36R and the first medication under development to specifically target the IL-36 pathway for the treatment of acute GPP