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NLRP3 inflammasome is formed due to hyperglycaemia and hyperlipidaemia, which promote pro-inflammatory cytokines by upregulating IL-1, IL-6 and IL-18, leading towards exacerbation of DCM pathology (134)

(Li et al., 2018) demonstrated for the first time that ferroptosis occurred in the collagenase-induced ICH mouse model, and ferroptosis was observed in neurons within the 1mm range of the edge from hematoma by transmission electron microscopy

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