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Older adults are often encouraged to get B-12 from supplements or fortified foods to prevent deficiency

Evidence levels range from FDA-approved (for narrow indications) to purely preclinical

They are however, not a cure and may have potential side effects with repeated use

Previous data demonstrating umbilical cord vitamin B and related metabolite amounts 2- to 6-fold higher than maternal serum concentrations are also suggestive of a high fetal demand for these nutrients (32)

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Acta Neurol Taiwan 14:4854 Alvarez M, Prieto AE, Portilla N, Moya D, Rincon O, Guzman I (2025) Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy