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Chapter one - assays for protein retrotranslocation in ERAD, in Methods in enzymology

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SAM administration may diminish oxidative stress by GSH synthesis, attenuate the inflammatory process by decreasing TNF- levels, and increase the biosynthesis of interleukin-10 [90]

Trkb Penk-KO , 1.06 0.25, p = 0.87 ) and GSH:GSSG ( Trkb Penk-WT , 1:00 0.23

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Neurological symptoms represent a significant concern with B12 deficiency and may include: Paraesthesia (pins and needles) in the hands and feet Difficulty with balance and coordination Memory problems or cognitive changes Mood disturbances , including depression or irritability Glossitis (sore, red tongue) and mouth ulcers Haematological manifestations of B12 deficiency include megaloblastic anaemia , characterised by the production of abnormally large, immature red blood cells