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Intriguingly, despite structural similarity to 5-HT, neither 5-HTP nor 5-HIAA confers protection against ferroptosis-inducing stimuli (e.g., RAS-selective lethal 3 exposure or GPX4 inactivation) (Liu et al., 2023)

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Animals were exposed to a gas mixture of 5% O 2 and 95% N 2 (mixed by volume) for 20 min to induce global hypoxia

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