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Expression was measured by qRT-PCR analysis and expressed relative to Ctrl WT (n=4 biologically independent samples)

A single application of the selected formulation (Dose approximately equivalent to 40 g LUT either in MN or applied gel matrix) was applied locally to the right eye of each rabbit, while the left eye, which received no treatment, served as the positive control

MK-677 follows closely at $160-220 monthly, though pricing varies significantly between suppliers

Prommer, 2017)

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Physician Assistants (PAs): Licensed to prescribe medications under the supervision of a physician, depending on regional regulations