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And human beings are going to have to adapt

aeruginosa , a common gram-negative bacterium, is an important pathogenic factor that causes serious infections in humans

The key mutation involves the oxidative modification of guanine to form 8-oxoguanine (8-oxo-G) in DNA, termed 8-oxo-7-hydro2-deoxyguanosine (8-oxo-dG) (see Fig

Choi J, Bae S, Lim H, et al

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Such activity can be directed toward pathogens, but also toward stressed (yet viable) neurons and synapses ( At the same time, the neuroglia may be rendered reactive or dysfunctional by processes not necessarily understood as inflammatory for instance through activation from abnormal vagal input or abnormal GPCR signaling (VanElzakker, 2013