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Priming is dispensable for NLRP3 inflammasome activation in human monocytes in vitro

Without treatment, this draining condition can make it difficult to live a full and active life

Furthermore, a reduction in symbiotic bacteria such as Faecalibacterium prausnitzii and overgrowth of pathogenic bacteria have been observed in the gut of IBD patients, with host-associated gene mutations impairing the recognition and clearance of the gut microbiome

De Moraes et al., 2012)

(1) Hippocampal CA1 Region Analysis of Iba1 fluorescence intensity revealed significant differences in microglial activation in the hippocampal CA1 region (Figs