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In patients with AD and PD, glial fibrillary acidic protein (GFAP) released from active astrocytes and ionized calcium-binding adaptor molecule 1 (Iba1) from active microglia under neuroinflammation are associated with loss of myelin and increased soluble tau level in neurons [63]

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Thus, the use of A20-deficient mice selectively on microglia generates an EAE model of early onset and aggravated pathogenesis

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This high energy demand creates a byproduct of oxidative stress

Anemia occurs when an individual consumes a diet rich in polyphenols or takes supplements containing these compounds (600)