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Brain lesions in rats that received cuprizone diet, and then cuprizone intragastrical applications, and thereby, cuprizone toxicity manifestations

Originally from Australia, Toni obtained her medical degree from the University of Adelaide

Histological analysis further supported these behavioral findings, showing partial restoration of tyrosine hydroxylase staining in the substantia nigra of Dihexa-treated animals, indicative of neuronal protection and recovery [2]

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Glucose also plays a key role, as it enters cells through GLUT1 and GLUT4, with insulin enhancing glucose uptake by promoting GLUT4 translocation to the cell membrane