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Jarvis R, Dobbs P, Moittie S, Liptovszky M, Baiker K et al (2022)

We sought to assess the impact of AKI response to treatment on survival and liver transplantation (LT) for patients with cirrhosis waitlisted for LT

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Importantly, FOXO4-DRI showed no significant toxicity or impact on viability and apoptosis in normal TM3 Leydig cells, where FOXO4 expression is typically low

Chronic activation of astrocytes and microglia leads to the release of cytokines involved in inflammation, chemokines, and other inflammatory mediators

J Free Radicals Biol Med