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Gastrointestinal side effects are dose-dependent and largely preventable through gradual escalation. Jastreboff et al., Nature Medicine 2

LD alone, however, failed to improve obesity-linked liver pathologies 13

First, deficiency is common in gut disease chronic enteropathy and exocrine pancreatic insufficiency impair absorption, so cobalamin must be replaced

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Most of these papillary thyroid carcinomas were less than 1 cm in greatest diameter and were diagnosed after thyroidectomy, which was prompted by finding on protocol-specified screening with serum calcitonin or thyroid ultrasound