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Because this peptide occurs naturally in the body, researchers had something to compare it against from day one

Tiggrin is a 220kd connector protein at muscle attachment sites

Engineering the cells to over-express phosphatase-regenerating-liver-1 further amplified platelet-derived growth factor cascades, thickened vessel walls and enhanced pericyte recruitment, highlighting how targeted gene editing can potentiate PD-MSC-mediated angiogenesis [181]