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Results timeline: Reduced inflammation and initial pain relief are commonly reported within the first 1-2 weeks

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even big men don't need more than 65 grams (about 2 ounces) a day, though athletes and men recovering from illnesses or surgery might do well with about 20% more

[15] In several instances the symptoms are exacerbated by drugs which induce cytochrome P450 (CYP) enzymes, leading to subsequent induction of -aminolevulinate synthase 1 (ALAS1), the first and rate-limiting enzyme in heme biosynthesis.[20] Under normal conditions, the activity of ALAD is present in excess and a partial deficiency of the enzyme (~50%) is not associated with disturbances of heme synthesis

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