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Pyrrolidine dithiocarbamate activates akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden

MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

Glutathione is heavily concentrated in the liver, and during alcohol metabolism is consumed rapidly as it neutralises toxic by-products and free radicals

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Research has demonstrated the involvement of ferroptosis, mitophagy, and CMA in the pathological progression of Osteoarthritis (OA)

Algorithms based either on a selection of biomarkers measured sequentially or, multiple biomarkers analyzed simultaneously and then combined into a single diagnostic indicator, are both approaches that are used to circumvent the inherent limitations of each individual biomarker