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[DOI] [PubMed] [Google Scholar] 391.Rezvani K, Rouce R, Liu E, Shpall E

1 H NMR (400 MHz, DMSO- d 6 ) 12.23 (s, 1H), 10.92 (s, 1H), 7.61 (d, J = 7.4 Hz, 1H), 7.537.39 (m, 2H), 7.33 (d, J = 8.7 Hz, 1H), 6.65 (d, J = 4.8 Hz, 1H), 5.06 (dd, J = 13.3, 5.0 Hz, 1H), 4.24 (dt, J = 34.4, 17.5 Hz, 3H), 4.07 (d, J = 20.2 Hz, 1H), 3.96 (d, J = 14.9 Hz, 2H), 3.76 (d, J = 12.4 Hz, 1H), 3.55 (t, J = 6.4 Hz, 2H), 3.513.42 (m, 8H), 3.17 (d, J = 6.4 Hz, 2H), 2.91 (d, J = 14.8 Hz, 1H), 2.852.77 (m, 1H), 2.64 (d, J = 11.6 Hz, 1H), 2.622.45 (m, 3H), 2.37 (d, J = 13.4 Hz, 1H), 1.981.89 (m, 1H), 1.73 (d, J = 11.6 Hz, 2H), 1.51 (d, J = 11.2 Hz, 1H), 1.34 (d, J = 13.0 Hz, 1H), 1.11 (d, J = 5.2 Hz, 9H)

Endocrine Signaling Research

This mechanism closely aligns with conventional antidepressant pharmacology, although Rhodiola exerts its effects within a broader adaptogenic framework rather than via selective receptor or transporter blockade

Adrian Sturza is a member of the Editorial Board of the same journal

Moreover, the regulation of T-cell and microglial activity by short-chain fatty acids further strengthens the neuroprotective effects of IF on the neuroimmune system (1922)