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In IBD, acetyl-L-carnitine improves immune tolerance by decreasing the ratio of Th17 cells and macrophages.[ref] Inborn errors of metabolism: Genetic mutations and carnitine Genetic mutations in the genes involved in the carnitine shuttle can cause inborn errors of metabolism for long-chain fatty acids

doi: 10.1016/S0093-691X(99)00278-2

In patients with diabetic retinopathy, abnormal carnitine metabolism may exacerbate oxidative stress and inflammation in the retina and promote the development of the disease [317]

10.1186/s12986-020-00535-y 86

Sodium selenite-induced apoptosis in murine B-lymphoma cells is associated with inhibition of protein kinase C-delta, nuclear factor kappaB, and inhibitor of apoptosis protein

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