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The number of animals to be used in the experiments (sample size) was determined by power analysis, where the largest estimated mean body weight difference between groups was 22 g, standard deviation was 10 g, type 1 error () was 0.05 and type 2 error () (Power = 0.80) and the number of groups was 5

doi: 10.1016/j.bcp.2013.06.022 16 PincinatoECCostaEFDLopes-AguiarLNogueiraGASLimaTRPVisacriMBet al

Grolez G, Moreau C, Sablonnire B, Garon G, Devedjian JC, Meguig S, et al

10.1016/j.clinbiochem.2012.06.016 107 HudsonC

Elevated plasma miR-133b and miR-221-3p as biomarkers for early Parkinsons disease

As a synthetic drug substance it does not qualify as a legal dietary supplement