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Data were collected from at least 10,000 cells

Recent advances in nanotechnology have yielded multifunctional platforms incorporating GSH-responsive linkages, redox-active metals, and prodrug designs with strong promise for targeted delivery and theranostics

Ensuring adequate glutathione levels is essential for supporting liver detoxification processes and reducing the impact of alcohol-induced toxicity

Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system

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Additional alterations manifest in ether-linked phospholipids, cholesterol esters, and glycosylated sphingolipids, with particular disruption of membrane cholesterol distribution crucial for CFTR protein trafficking (Dei Cas et al., 2020